Meanwhile, Indians manager Manny Acta hopes his lineup builds off Tuesday's late rally -- though it fell short -- following a rash of injuries and the relegation of Travis Hafner to a pinch-hitting role in National League parks.
The D-backs' recent skid cost them a share of the division lead in the face of the Giants' seven-game winning streak, continuing what has been a fairly streaky season for Kirk Gibson's club. However, Arizona's skipper remains confident that his team will dig out of its brief lull.
"I think we compete well, we fight through disappointment well. We're developing nicely, and we're in a stretch here that's going to test our character a bit. But I feel we're well prepared for that," Gibson said.
"It goes in cycles. Every team will probably go through periods where things don't go as they'd like them, but you have to endure them. The Giants lost 4-5 in a row, now they're on a run. So that's what we're going to try to do."
Acta knows what it's like for his team to go through cycles, after his club's hot start and subsequent cold spell that coincided with stints on the disabled list by Travis Hafner, Grady Sizemore, Shin-Soo Choo and others.
Nevertheless, the lineup will attempt to support Carlos Carrasco, who has been one of the American League's most effective pitchers over the last three weeks. The right-hander is 3-1 in his last four starts, having allowed just two earned runs over his previous 29 2/3 innings. It was the Giants who handed Carrasco a loss in his last outing, though he gave up just one earned run over eight innings with four strikeouts and no walks.
Veteran Zach Duke will take the hill for the D-backs in the series finale. He has struggled to find his rhythm after missing the first two months of the season with a broken hand. In his last outing, he allowed six runs on seven hits in just four innings against the Tigers.
Indians: Choo out at least two months
Choo's disappointing season took another negative turn on Friday when he suffered a left thumb fracture. He underwent surgery on Tuesday and will be sidelined for eight to 10 weeks. Choo, who is hitting .244 with five home runs and 28 RBIs, is disheartened by the injury and his inability to help the Indians push through the summer months.
"I just feel bad that I can't help the team anymore," Choo said on Saturday. "We might make the playoffs. We had a good start, and I can't help the team. I feel sad."
D-backs: Upton heating up in summer
Justin Upton has been one of the most prolific hitters dating back to late-May. Since May 29, Upton is hitting .418 (46-for-110) with an on-base percentage nearing .500. He is also tied for third in all of baseball with 10 doubles to go along with with 68 total bases.
While his home run total has dropped significantly in June -- with only one of his 12 home runs coming so far this month -- his RBI production has remained extremely consistent. Upton has knocked in 14 runs this month, after driving in 14 in April and 14 May. The outfielder is also tied for the Major League lead with 70 hits in Interleague Play dating back to 2008.
Tuesday's walk-off win pushed the D-backs to 40-0 in games in which they hold a lead after the eighth inning.